The concentration of platelets and other factors in PRP is 5–10 times higher than that of conventional autotransfusion, which can effectively avoid the loss of platelets and fibrinogen, coagulation factor V, coagulation factor VIII, and other coagulation components [26], and PRP has been confirmed as a promising and safe method for the musculoskeletal diseases, which repairs tissues with poor healing capacity [27]. The gene discussed is F8; the disease is musculoskeletal system disorder.