ERBB2 and esophageal squamous cell carcinoma: Moreover, rs12976445 leads to a poor prognosis of esophageal squamous cell cancer, whereas a past report demonstrated that the level of mature miR-125a is reduced by rs12976445 G- > T, thus reducing the inhibitory effects of miR-125a on its downstream targets, such as ERBB2 and LIFR48–50.