We showed that the SOX2 reprogramming TF that drives GBM cell stemness and tumor-propagating potential induces miR-10b-5p (Fig. 3) that targets TET2 (Fig. 4 and Supplementary Fig. 12) that we show inhibits GBM cell stemness and GBM xenograft growth (Fig. 2). Here, TF is linked to glioblastoma.