A recent RNA sequencing study identified two microRNAs (miR) involved in infarction (MI), miR-30-5p downregulated and miR-142a-5p upregulated respectively in MI, and the vitro experiment demonstrated that miR-30-5p is anti-apoptotic and miR-142a-5p is pro-apoptotic; then their luciferase assays displayed that the Picalm and Skil (apoptotic genes), and the Ghr and Kitl (anti-apoptotic genes) are direct targets of miR-30-5p and miR-142a-5p, respectively [41]. This evidence concerns the gene PICALM and myocardial infarction.