MKNK1 and non-small cell lung carcinoma: To investigate the clinical significance of miR-7-5p and MNK1 in NSCLC tissues, we firstly confirmed the lower levels of miR-7-5p in 34 cases of NSCLC tissues compared with paired adjacent tissues by qPCR (Fig. 3A), while the mRNA of MNK1 was significantly increased in NSCLC tissues than that in paired adjacent lung tissues (Fig. 3B).