We further detected miR-7-5p by in situ hybridization and MNK1 protein by immunohistochemistry in 318 cases of paraffin-embedded NSCLC tissues (including 161 cases of lung adenocarcinoma and 157 cases of lung squamous cell carcinoma) and 90 cases of adjacent lung tissues respectively. Here, MKNK1 is linked to squamous cell lung carcinoma.