PTBP3 and colorectal carcinoma: Additionally, PTBP3 expression was detected in 5 human CRC cell lines (HT-29, HCT116, SW480, SW620 and LoVo) and normal human colonic epithelial FHC cells, and PTBP3 expression was significantly higher in cancer cell lines than in FHC cells (Fig. 1E, F).