In contrast, in an assay using DARA-treated CD38+ NCI-H929 myeloma cells, CD38KO NK cells transfected with CD16-158V mRNA displayed greater cytotoxicity than both CD16-158V-transfected CD38WT NK cells and non-transfected CD38KO NK cells (figure 4D). The gene discussed is CD38; the disease is plasma cell myeloma.