By evaluating the largest cohort of genetically confirmed dysferlinopathy cases reported to date and comparing them to similar numbers of Becker muscular dystrophy, calpainopathy, and inflammatory myopathy cases, this study demonstrates that the number of inflammatory cell clusters and total number of inflammatory cells are similar in the muscle biopsies from DYSF, CAPN3, and BMD patients. This evidence concerns the gene CAPN3 and Becker muscular dystrophy.