CLIC1 and glioblastoma: In particular, CLIC1 regulates cell cycle progression, proliferation, migration and apoptosis in several solid tumors [2, 3] including melanoma, colorectal, lung, ovarian, pancreatic, prostate, and breast cancer, [4], and glioblastoma (GBM) [5–7], and was proposed as prognostic biomarker and therapeutic target [3, 8].