As we discovered that cPLA2 inhibitor treatment was significantly effective only in the DOX-inducible mouse model of mS100a7a15, therefore in this study, we investigated the anti-tumor effect of AACOCF3 on immune response mediated through CD4+ and CD8+ TILs in mS100a7a15 overexpression group using CODEX. This evidence concerns the gene CD8A and neoplasm.