CADM1 and type 1 diabetes mellitus: As expected, CADM1 was detected at the plasma membrane throughout the endocrine pancreas in sections from the Non group, and the number of CADM1+CD45+ cells was elevated in the aAb+ and T1D groups, indicating a significant number of islet leukocyte cells were CADM1+ (Figure 3, B–D) (21).