CADM1 and type 1 diabetes mellitus: Together, these results show (a) increased numbers of CADM1+ myeloid cells within the islets of aAb+ human donors and donors with T1D, and (b) strong colocalization of CADM1 with insulin adjacent to CADM1+ myeloid cells implies potential CADM1-mediated binding between immune and islet endocrine cell types.