Furthermore, quantification of CD68+ cells at the islet periphery or within the islet also showed that CD68+ cell numbers were elevated in both the aAb+ and T1D groups (Figure 4, C and D), and CADM1+CD68+ cell numbers were similarly increased in these groups compared with the Non group (Figure 4E). The gene discussed is CADM1; the disease is type 1 diabetes mellitus.