VEGFA and chronic kidney disease: Glomerular VEGF levels significantly elevated by 2- to 3-fold in a subset of Medalists protected against CKD (eGFR > 70 mL/min/1.73 m2) compared with a subset with lower eGFR (eGFR < 45 mL/min/1.73 m2) (Figure 4C and Supplemental Table 1).