Proteins were quantified in plasma with a highly multiplexed proteomic assay (SOMAscan); 361 proteins including creatine kinase myocardial band (CK-MB), hepcidin (HEPC), phospholipase A2 group IIA (PLa2G2A) and myosin-binding protein C (MYBPC1) were differentially expressed between TB progressors and non-progressors before the onset of symptoms. This evidence concerns the gene MYBPC1 and tuberculosis.