MMRN1 expression is significantly downregulated in 17 (bladder, breast, colon, oesophagous, liver, lung (adenocarcinoma and squamous cell carcinoma), ovary, prostate, rectum, renal (cell carcinoma and papillary cell carcinoma), skin, stomach, testis, thyroid, uterus (uterine carcinosarcoma and uterine corpus endometrial carcinoma)) out of 22 cancer types, and significantly upregulated in acute myeloid leukaemia and pancreatic cancer (TNM plot pan-cancer analysis [47]). The gene discussed is MMRN1; the disease is cancer.