While certain genes were specific to the individual injury model — e.g., Slfn4 specific to chronic H. pylori infection (43) and Erdr1 specific to HD-Tam — and not previously shown to our knowledge to be involved in the dsRNA response, a substantial subset of genes related to the dsRNA response was upregulated to a nearly identical extent across both models (Figure 2B). The gene discussed is STIM1; the disease is Huntington disease.