In the SERPINE1 high expression group, the eight most significantly enriched signal pathways were cytokine cytokine receptor interaction, extracellular matrix receptor interaction, focal adhesion, hypertrophic obstructive cardiomyopathy, JAK-STAT3 signal pathway, MAPK signal pathway, and cancer pathway (Figures 3(a)–3(i)). The gene discussed is STAT3; the disease is cancer.