In RCC patients with ≥5% tumor cells staining positive for PD-L1, sPD-L1 level was generally higher (p=0.074), but otherwise, we saw no association between baseline sPD-L1 and the percentage of PD-L1-positive tumor cells in biopsies obtained at baseline (figure 1C). The gene discussed is SPDL1; the disease is neoplasm.