than control cells, whereas overexpression of KChIP3 renders cancer cells almost 10 times more sensitive to the chemotherapy (IC50 control cells = 2.9 μg/mL, KChIP3-KD cells = 13.4 μg/mL, KChIP3-OV = 0.3 μg/mL) (Figure 2D). Here, KCNIP3 is linked to cancer.