CTLA4 and mesothelioma: Recently, the first-line phase 3 CHECKMATE-743 study of cytotoxic T lymphocyte antigen 4 (CTLA-4) and programmed death receptor-1 (PD-1) blockade with ipilimumab and nivolumab respectively versus standard chemotherapy in non-resectable mesothelioma reported a median overall survival of 18 months for the former with FDA approval on October 2nd 2020 [1].