ESR1 and anxiety disorder: In terms of specific diagnoses made by a clinical behaviorist, we detected three significant marker associations with anxiety disorder: chr1 near ESR1, chr20 near MITF and chr24 near RALY, EIF2S2 and ASIP. The relevant mapped traits were fear of unfamiliar dogs for Chr1A, separation urination and separation anxiety for Chr20, and nonsocial fear, touch sensitivity and separation anxiety for Chr24A (Suppl.