Most common AEs were blood and lymphatic system disorders (lymphocytosis, neutropenia), hepatobiliary disorders (hyperbilirubinemia, transaminases increased, gamma glutamyl transpeptidase (GGT) increased), cardiovascular disorders (arterial hypertension), and infections (respiratory tract infections, tonsillitis, urinary tract infection). This evidence concerns the gene GGTLC1 and Respiratory tract infection.