In earlier studies, IL-8 receptor CXCR1 was found to be associated with hepatic inflammation,35 while Ruminococcus has been linked to liver fibrosis.36 Previously reported deregulated autochthonous taxa Faecalibacterium and Roseburia37 were also associated with increased levels of IL-8 in the hepatic blood of patients in our cohort. This evidence concerns the gene CXCR1 and Hepatic fibrosis.