For Caspase9 expression,the CIS+EPI group showed a higher increase than EPI (p < 0.05; Figure 6C) in the SKBR3 cell line, and the Mfn1 expressionlevel in 4T1 cells for CIS+EPI was higher than that for EPI (p < 0.01; Figure 5D). Here, MFN1 is linked to in situ carcinoma.