For instance, there were five traits with evidence to support an effect on liability to type 2 diabetes (whole-body fat-free mass, whole-body water mass, peak expiratory flow, lymphocyte count, IGF-1) but not liability to coronary or peripheral artery disease, as well as 12 and eight traits with specific effects on liability to coronary and peripheral artery disease, respectively. The gene discussed is IGF1; the disease is type 2 diabetes mellitus.