KCNH2 and neoplasm: Gamitrinib IC50 for hERG conductance in patch-clamp studies (3.5 μM) was up to 20-fold times higher than the IC50 of inhibition of tumor growth observed in an NCI 60-cell line screen,28 and only 1 out of 10 animals exhibited a small, 7% prolongation of QTc interval (17 msec) fully reversed during the recovery phase.