The RT-qPCR result suggested that the RNF2 expression was increased in the tumor tissues compared to the normal tissues (p < 0.0001) (Figure 6(d)), which presented an inverse association with miR-149 while a positive association with DNMT3B (p < 0.0001) (Figure 6(e,f)). This evidence concerns the gene RNF2 and neoplasm.