MKI67 and neoplasm: In addition, the IHC of tissue sections suggested that the levels of KI67 and PCNA (tumor proliferation markers) in cells was declined by miR-149 mimic (p < 0.0001) (Figure 3(c,d)), and the portion of TUNEL-positive cells in tissues was increased (p < 0.0001) (Figure 3(e)).