IFNG and steatosis: It has been reported that stimulation of TNFRSF9 with agonistic antibody reduces adiposity, body weight, and HS and increases energy expenditure in diet‐induced obese mice and genetically obese/diabetic mice.[42] The plasma level of ST1A1, IFN‐gamma, and CCL23 was lower only in mild steatosis versus no steatosis (Figure 5B).