Genes strongly associated with T2DM include TCF7L2 (involved in insulin secretion and glucose production), ABBC8 (regulates insulin), CAPN10 (involved in insulin sensitivity and secretion), GLUT2 (transports glucose into pancreatic β cells), GCGR (involved in glucagon regulation) (Naseri et al., 2020) and others (Naseri et al., 2020; Park, 2011). This evidence concerns the gene INS and type 2 diabetes mellitus.