PPARG and Alzheimer disease: Studies with mouse models of both T2DM and AD demonstrate that activating peroxisome proliferator‐activated receptor γ (PPARγ) and the adenosine monophosphate (AMP)‐activated protein kinase (AMPK) pathways significantly increase IDE leading to decreased Aβ levels and rescue of recognition and learning memory deficits (Li et al., 2018).