Obese MAFLD patients were younger, had lower levels of postprandial glucose and shorter diabetic duration, had greater levels of AST, ALT, fasting insulin, postprandial insulin, TG, HOMA-IR index, and TyG index, and had higher percentages of individuals with hypertension and dyslipidemia histories than subjects with lean or nonobese MAFLD (all P < 0.05). The gene discussed is GPT; the disease is metabolic syndrome.