Moreover, further determination of Bax and Bcl-2 protein expression by IHC revealed that the expression level of pro-apoptotic protein Bax was decreased while that of anti-apoptotic Bcl-2 was obviously elevated in quadriceps muscle tissues of mice in Swimming group, which compared with Tumor group (Figure 4B, #p < 0.05 vs Control group; *p < 0.05 vs. Tumor group). Here, BAX is linked to neoplasm.