TNF and hydrops fetalis: Furthermore, lentinan supplementation inhibited the mRNA of the proinflammatory cytokines and chemokines, TNFα, IL-1β, IL-6, and monocyte chemoattractant protein-1 (Mcp1) compared with HF mice (all p < 0.05, Figure 4H) and increased the expression of antiinflammatory cytokines, IL-10, and arginase I (Arg1) (both p < 0.05, Figure 4H).