Previously, our cross-sectional study revealed significantly higher levels of serum amyloid A (SAA), interleukin (IL)-6, IL-8, IL-18, IL-23 and chitinase 3 like protein 1 (CHI3L1) in sera of therapy-naïve GCA patients compared to HBDs, reflecting an active disease (22). The gene discussed is CHI3L1; the disease is temporal arteritis.