Next, we examined the potential effects of tauopathy in sevoflurane-induced pyroptosis by analyzing cell protein samples and found that Aβ (1.6-fold) and p-tau (1.8-fold) levels were elevated after sevoflurane exposure (Figures 4A,B) compared with the control and LPS groups (Figures 4C,D). This evidence concerns the gene MAPT and tauopathy.