It was shown that PNPO expression was significantly correlated with six types of infiltrating immune-associated cells including B cell, CD8+T cells, CD4+T cells, neutrophils, macrophages, and dendritic cells in BRCA, GBM, KICH, LIHC, SARC, STAD, THCA, and THYM (Supplementary Figure S6). The gene discussed is CD4; the disease is glioblastoma.