Studies have identified that stromal-specific loss of p53 acts through CXCL17 to effect M2 TAMs differentiation, MDSCs infiltration, and CD11b+Gr1+ MDSCs recruitment that conspire to enhance tumor growth (Ryan et al., 2000; Guo et al., 2013; Bezzi et al., 2018). Here, ITGAM is linked to neoplasm.