In conclusion, we systematically demonstrated the molecular process of aneuploidy in PCa and identified 11 potential driver genes (GSTM2, HAAO, C2orf88, CYP27A1, FAXDC2, HFE, C8orf88, GSTP1, EFS, HIF3A, and WFDC2). The gene discussed is GSTM2; the disease is posterior cortical atrophy.