GACAT3 is a promising biomarker for CRC as it is overexpressed in CRC tissues and is upregulated in the CRC cell lines HT29, HCT116, SW480, and LoVo relative to the normal colorectal epithelial cell line FHC (Zhou et al., 2018; Ye et al., 2020). The gene discussed is GACAT3; the disease is colorectal carcinoma.