In addition to kidney cancers, other human cancers also showed significant alterations in PAQR5 gene expression, including upregulation in cancers from the breast, bile duct, liver, and uterine corpus, and downregulation in cancers from the colon, brain, lung, adrenal gland, prostate, rectal, and thyroid organs (Supplementary Figure S2). Here, PAQR5 is linked to cancer.