ENTPD1 and breast carcinoma: Propofol attenuated the decrease in CD39 and CD73 in circulating CD4+ T cells compared to sevoflurane-based anesthesia in patients undergoing open heart surgeries (23), while similar comparative studies have not been reported in breast cancer patients despite that circulating regulatory T cells has been recently reported to be significantly increased in breast cancer patients which may impact on the stage and histological type of breast cancer (24).