In agreement with the tumor volumes, the weight of tumors derived from OSBP2-knockdown ASPC-1 cells was significantly lower than that of tumors derived from control ASPC-1 cells, and the weight of tumors derived from OSBP2-overexpression BXPC-3 cells was significantly higher than that of tumors the control (P <0.05; Figure 6B). The gene discussed is OSBP2; the disease is neoplasm.