Researchers put particular focuson three TGFB1 gene polymorphisms associated with cardiovascular diseases:rs1800469 is localized in the promoter region, and rs1800470(leucine-to-proline substitution in codon 10) and rs1800471(arginine-to-proline substitution in codon 25) are localized in the codingregion. This evidence concerns the gene TGFB1 and cardiovascular disorder.