After the analysis, 19 significant therapeutic pathways including epithelial cell signaling in Helicobacter pylori infection, proteoglycans in cancer, FoxO, GnRH, estrogen, pathways in cancer, Ras, prolactin, MAPK, TNF, Rap1, thyroid hormone, neurotrophin, sphingolipid, oxytocin, VEGF, Fc epsilon RI, insulin resistance, and hepatitis C were identified. The gene discussed is TNF; the disease is cancer.