In this study, it was found that cancers with high ACSL4 expression (LICH, COAD, STAD) had high levels of MDSC infiltration, while cancers with low ACSL4 expression (BRCA, KIRC, LUSC, SKCM) had high levels of MDSC infiltration, and had poor prognosis and survival in BRCA and SKCM. Here, ACSL4 is linked to cancer.