The results of pathway enrichment analysis showed that the PI3K-Akt pathway was related to SCN7A. The PI3K-Akt pathway has been proven both in vitro and in vivo to participate in the progression of many types of cancer (Chamcheu et al., 2019; Ediriweera et al., 2019; Lee et al., 2020). The gene discussed is SCN7A; the disease is cancer.