CALR and Sjogren syndrome: Primary Sjogren’s syndrome (pSS) is characterized by the presence of circulating autoantibody (anti-Ro/SSA and anti-La/SSB), as well as the involvement of the exocrine glands (salivary and lacrimal gland), joint, and muscle (Nossent et al., 2012; Haldorsen et al., 2013).