Interestingly, another study also showed that phosphorylation of the SRSF6 splicing factor by DYRK1A modulates the splicing of cardiac troponin T (TNNT2) variants, promoting the inclusion of exon five into TNNT2 in Ts65Dn mice, another murine DS model (Lu and Yin, 2016). The gene discussed is TNNT2; the disease is Dravet syndrome.