CYCS and Thrombocytopenia: So far, there are only 4 pedigrees with nonsyndrome thrombocytopenia and 1 pedigree with hemophilia A, associated with variants in CYCS gene (Morison et al., 2008; De Rocco et al., 2014; Johnson et al., 2016; Uchiyama et al., 2018; Turro et al., 2020).