The strongest expression–trait associations for asthma were observed at PNMT (phenylethanolamine N-methyltransferase) on chromosome 17 (the strongest association at the adipose visceral omentum, PTWAS = 6.58 × 10−46), which catalyzes the synthesis of epinephrine from norepinephrine (Mahmoodi et al., 2020). The gene discussed is PNMT; the disease is asthma.