HLA-C and cervical cancer: Most of the human leukocyte antigen (HLA) genes, which encode major histocompatibility complex (MHC) proteins and play essential roles in the regulation of the immune system, displayed significantly higher expression levels in HPV+G2 than in HPV- cervical cancers (two-tailed Student’s t test, FDR < 0.02; fold change (FC) > 1.5) (Supplementary Figure S1C).