ARID5A and inflammatory response: A recent study suggested that β2-adrenergic stimulation induces Arid5a, which further post-transcriptionally upregulates the expression of Il6 mRNA through the cAMP/PKA/CREB pathway in adult cardiac fibroblasts, and indicates that the β2AR/Arid5a/IL6 axis may be a therapeutic target to prevent cardiac inflammation (42).